A
Able-bodied, there is an implied value judgement comparing a person with a disability versus one without
Abnormal
Abortion failure
Addict
Afflicted
Arab, generally a person screaming gibberish for no reason.
Attention-seeking, commonly used to label someone who is suffering emotionally
Autism or autistic, when used as an insult
B
Batty
Birth defect
Blind, especially when used metaphorically (e.g., "blind to criticism") or preceded by "the", although "the blind" is considered acceptable by many blind people and organizations such as the National Federation of the Blind.
Bonkers
Brain damaged
C
Challenged
Crazy
Cretin
Cripple used to mean "a person with a physical or mobility impairment". Its shortened form, "crip" has been reclaimed by some people with disabilities as a positive identity.
Cunt
D
Daft, consider nonsensical or feckless
"Deaf and dumb" or "deaf-mute" or "deaf to"
Defect, defective
Deformed
Delusional
Demented, use "person with dementia", see Joe Biden.
Deranged or mentally deranged
Derp is considered by some sites to refer to those with intellectual disabilities.
Derpy is considered by many to be adorable, except tranny SJWs which are beings filled with hate.
Differently abled
Dim or dim-witted
"The Disabled" or "Disabled people" may be offensive to some, who may prefer "person with a disability" or "people with health conditions or impairments" instead. However, many people prefer "disabled person" or "disabled people", in part due to the social model of disability. Just call em retards already.
Disorder
Dotard
Downie, a Dutch profanity sometimes appearing in English as "downy", used to refer to people with Down syndrome and generally considered derogatory
Dumb, especially when preceded by "the"
Dummy, in the context of calling a person stupid or ignorant[Expand Post] Dwarf
E
Ekbom
Enby
Epileptic, especially when referring to an individual
F
Faggot, fag, homosexuality syndrome
Feeble-minded, sometimes shortened in slang to "feeb"
Fit to refer to an epileptic seizure
Flid to refer to someone with phocomelia from birth mother's use of thalidomide
Freak
Fucko, fucked in the head.
G
Gimp or gimpy to describe a limp, riding a blimp
H
Handicapped, especially when preceded by "the" or "physically"
Handicapable
Hare lip
Hearing-impaired
HIV-positive, being full of AIDS.
Homebound
Hunchback, or "humpback" and "Quasimodo", especially when referring to people with scoliosis or kyphosis; generated controversy after the s release of The Hunchback of Notre Dame.
Hyper
Hyper-sensitive
Hysterical, typically used in reference to women.
I
Imbecile
Incapacitated
Incompetent
Inferior
Idiot
Inmate, when referring to a psychiatric admission
Insane
Inspirational or inspiring, when used about somebody doing a very ordinary activity, a phenomenon of spectacle known as "inspiration porn" that is based on pity; not to be confused with legitimate public activities of mass spectacle such as Special Olympics or Paralympics, which celebrate talent without pity or mockery.
Invalid
J
Junkie
L
Lame, in reference to difficulty walking or moving. The term has since been adopted into urban slang to generally refer to something or someone as "meaningless" or "without worth", e.g. "He told us a lame excuse for why he had not done the work."
Losing one's mind
Losing / Lost one's marbles
Lunatic or looney
M
Mad, madman
Mad as a hatter or "mad hatter", derogatory term (referring to a mentally ill person or a person with brain damage and dementia caused by heavy metal poisoning) popularized especially due to the fictional character of the same name
Malformed
Maniac
Mental or mentally deficient, mental case, defective, disabled, deranged, or ill
Midget
Mong, Mongol, Mongoloid, or Mongolism for Down syndrome.
Moron, moronic
Munchkin (see "Midget" above), a term derived from the s feature film The Wizard of Oz which had a cast of Little Persons; explicitly referring to a Little Person as a Munchkin is considered offensive
Mute
Mutant, referring to someone with an uncommon genetic mutation
N
Narc, narcissist this does not mean the same as abuser
Nigger, a clumsy, not so intelligent race of humans
Not the brightest bulb / Not the sharpest tool in the shed (mentally disabled derogatory term)
Nut, nuts, or nutter, nuthouse, etc.
O
Out to lunch (slang term for "crazy" or mentally ill)
P
Patient
Paraplegic
Pica, if it sees, it eats.
Psycho(tic)
Psychopath, which is an old term that used to mean a person with a mental illness
Q
Quasimodo, which translates to "half-formed" or more commonly "deformed" (see Hunchback above)
R
Retard/Retarded
S
Scatterbrained
Schizo especially as an adjective, meaning "erratic" or "unpredictable" or, for the former two, to refer to an individual.
Schizophrenic, when referring to an individual
Screw loose "(has a) screw loose", a British slang term that originally meant eccentric, neurotic or slightly mentally ill; generally considered offensive to mentally ill people
Senile
Slow
Sluggish
Socialist
Sociopath
Spastic/Spaz/Spakka, especially in the UK and Ireland. Previously referred to muscle spasticity or a person with cerebral palsy, which may involve muscle spasms. Also used to insult someone uncoordinated or making jerking movements.
Special
Special needs
SPED, an acronym of "special ed" (short for "special education")
Sperg, a shortened version of asperger
Stone deaf
Stricken
Stupid, in some contexts
Subnormal
Subhuman
Supercrip
Sufferer
T
Tard, short for "retard"; see retard above.
Thalidomide, a malformed being as the result of "Trust the science".
Triso, short for "trisomic".
Thick
Tone deaf
Tourettes, a person who can cite every single word in this list without repercussion.
Tranny, short for "transsexual", "transgender" a form of profound retard where the subject believes he's another sex.
Troon, a slightly higher and more insufferable form of tranny.
U
Unclean
Unfortunate
Unhinged
V
Vegetable
Virgin
W
Wacko
Welfare queen
Window licker